Keiko Naruse Selected Research

Diabetic Neuropathies (Diabetic Neuropathy)

1/2021	Sustainable Effects of Human Dental Pulp Stem Cell Transplantation on Diabetic Polyneuropathy in Streptozotocine-Induced Type 1 Diabetes Model Mice.
10/2020	Secreted Factors from Stem Cells of Human Exfoliated Deciduous Teeth Directly Activate Endothelial Cells to Promote All Processes of Angiogenesis.
10/2020	Deficiency of glucagon gene-derived peptides induces peripheral polyneuropathy in mice.
8/2020	Direct Comparison of Therapeutic Effects on Diabetic Polyneuropathy between Transplantation of Dental Pulp Stem Cells and Administration of Dental Pulp Stem Cell-Secreted Factors.
1/2020	Transplantation of human dental pulp stem cells ameliorates diabetic polyneuropathy in streptozotocin-induced diabetic nude mice: the role of angiogenic and neurotrophic factors.
1/2020	Secreted factors from cultured dental pulp stem cells promoted neurite outgrowth of dorsal root ganglion neurons and ameliorated neural functions in streptozotocin-induced diabetic mice.
9/2019	Conditioned media from dental pulp stem cells improved diabetic polyneuropathy through anti-inflammatory, neuroprotective and angiogenic actions: Cell-free regenerative medicine for diabetic polyneuropathy.
1/2019	Glucagon-Like Peptide-1 Receptor Agonist Protects Dorsal Root Ganglion Neurons against Oxidative Insult.
1/2019	Ranirestat Improved Nerve Conduction Velocities, Sensory Perception, and Intraepidermal Nerve Fiber Density in Rats with Overt Diabetic Polyneuropathy.
1/2019	Schwann Cells as Crucial Players in Diabetic Neuropathy.

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Keiko Naruse Research Topics

Disease

26	Diabetic Neuropathies (Diabetic Neuropathy) 01/2021 - 09/2002
8	Periodontitis 11/2020 - 04/2012
4	Diabetes Complications 01/2021 - 05/2007
4	Metabolic Syndrome (Dysmetabolic Syndrome X) 12/2018 - 03/2011
4	Inflammation (Inflammations) 07/2016 - 05/2013
4	Atherosclerosis 07/2016 - 08/2008
4	Insulin Resistance 06/2011 - 05/2003
3	Alveolar Bone Loss 11/2020 - 04/2012
3	Polyneuropathies (Polyneuropathy) 10/2020 - 09/2011
3	Obesity 12/2018 - 03/2006
2	Type 2 Diabetes Mellitus (MODY) 01/2021 - 10/2008
2	Hyperplasia 01/2019 - 02/2004
2	Cardiovascular Diseases (Cardiovascular Disease) 08/2010 - 05/2007
2	Coronary Disease (Coronary Heart Disease) 08/2010 - 05/2009
2	Stroke (Strokes) 08/2010 - 05/2009
2	Angina Pectoris 05/2007 - 01/2007
2	Myocardial Infarction 05/2007 - 11/2006
1	Neoplasms (Cancer) 01/2021
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2021
1	Tooth Loss 01/2021
1	Edema (Dropsy) 01/2021
1	Vascular Diseases (Vascular Disease) 10/2020
1	Body Weight (Weight, Body) 08/2020
1	COVID-19 07/2020
1	Bone Resorption 01/2020
1	Sensation Disorders 01/2019
1	Wounds and Injuries (Trauma) 09/2014
1	Periodontal Pocket (Periodontal Pockets) 05/2013
1	Hemorrhage 05/2013
1	Periodontal Diseases (Periodontal Disease) 05/2013
1	Nerve Degeneration 01/2013
1	Hypercholesterolemia 11/2012
1	Neuralgia (Stump Neuralgia) 01/2011
1	Hyperalgesia 01/2011

Drug/Important Bio-Agent (IBA)

10	Streptozocin (Streptozotocin)FDA Link 01/2021 - 05/2006
6	CytokinesIBA 01/2021 - 08/2010
6	NAD (NADH)IBA 10/2020 - 11/2008
5	Therapeutic UsesIBA 01/2021 - 10/2017
5	Insulin (Novolin)FDA Link 11/2020 - 01/2002
5	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 03/2003
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 01/2002
4	Aldehyde Reductase (Aldose Reductase)IBA 01/2019 - 09/2002
4	polyolIBA 01/2019 - 09/2002
4	Messenger RNA (mRNA)IBA 03/2014 - 02/2004
3	Nerve Growth Factor (NGF)IBA 01/2021 - 10/2008
3	Nitric Oxide Synthase (NO Synthase)IBA 11/2020 - 03/2006
3	Proteins (Proteins, Gene)FDA Link 01/2019 - 08/2008
3	AdiponectinIBA 11/2012 - 03/2011
2	Peptides (Polypeptides)IBA 10/2020 - 07/2016
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020 - 07/2016
2	Conditioned Culture MediaIBA 01/2020 - 09/2019
2	Glucagon-Like Peptide-1 ReceptorIBA 01/2020 - 09/2011
2	Nerve Growth Factors (Neurotrophins)IBA 01/2020 - 01/2019
2	epalrestatIBA 01/2019 - 03/2003
2	Nylons (Nylon)IBA 10/2017 - 04/2012
2	3-nitrotyrosineIBA 10/2017 - 04/2012
2	C-Reactive ProteinIBA 05/2013 - 11/2012
2	ResistinIBA 08/2010 - 05/2009
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 08/2010 - 11/2006
2	SaltsIBA 08/2009 - 05/2003
2	Antihypertensive Agents (Antihypertensives)IBA 08/2009 - 11/2006
2	Reactive Oxygen Species (Oxygen Radicals)IBA 02/2008 - 05/2007
2	Nicorandil (SG 75)IBA 05/2007 - 01/2007
2	Protein Kinase CIBA 03/2006 - 03/2003
1	alogliptinIBA 01/2021
1	ChemokinesIBA 01/2021
1	Dipeptidyl-Peptidase IV InhibitorsIBA 01/2021
1	Glucagon (Glukagon)FDA Link 10/2020
1	Blood Glucose (Blood Sugar)IBA 08/2020
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 01/2020
1	Liraglutide FDA Link 01/2020
1	Neutralizing AntibodiesIBA 01/2020
1	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2020
1	N 30IBA 01/2020
1	GlycogenIBA 01/2019
1	ranirestatIBA 01/2019
1	AdipokinesIBA 12/2018
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 10/2017
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 10/2017
1	gastric inhibitory polypeptide receptorIBA 07/2016
1	LipopolysaccharidesIBA 07/2016
1	lipopolysaccharide-binding proteinIBA 03/2014
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 05/2013
1	Tuberculin (PPD)IBA 05/2013
1	cyclopropapyrroloindoleIBA 05/2013
1	pitavastatin (itavastatin)FDA Link 11/2012
1	Exenatide (Byetta)FDA Link 09/2011
1	AcetoneIBA 01/2011
1	HDL CholesterolIBA 08/2010
1	Triglycerides (Triacylglycerol)IBA 08/2010
1	LDL CholesterolIBA 08/2010
1	CreatinineIBA 08/2010

Therapy/Procedure

15	Transplantation 01/2021 - 06/2005
6	Ligation 11/2020 - 04/2012
5	Therapeutics 08/2020 - 11/2006
4	Stem Cell Transplantation 01/2021 - 12/2017
4	Cell Transplantation 01/2019 - 11/2010
3	Glycemic Control 01/2021 - 05/2013
2	Percutaneous Coronary Intervention 01/2007 - 11/2006
1	Autologous Transplantation 01/2011